Everyone experiences Pain

Pain is a general reaction to stress, injury, discomfort or infection in the body; you are liable to experience pain in one part of the body or the other; because you can sustain any of the above.

Even at old age, pain becomes inevitable; becomes frequent even when no strenuous work is done or after light activities. Pain could be traumatic after a break from a consistent career period.

Ibuprofen in Pain management

In taking care of pains, prescribing guidelines stipulates that a single dose of a NSAIDs like Ibuprofen, Aspirin, Indometacin or Diclofenac is better than Paracetamol because of its beneficial effect in conditions like back pain, juvenile or rheumatoid arthritis, soft tissue disorder and menstrual pains.

Ibuprofen is widely used by the elderly, women in menstrual pain or after an accident of kids at school or even high temperature in infant. The place of ibuprofen cannot be over emphasized all over the world especially in Africa. It’s very expedient that everyone should know when you cannot take the drug or what shouldn’t be taken with Ibuprofen.

People that should not take ibuprofen

  1. People with Ulcer: If you have an active ulcer, you should stay away from Ibuprofen and consult your Pharmacist for an alternative for management of pain. Ibuprofen wears off the protective layer of the stomach by inhibiting prostaglandin (the substance responsible for protection of the stomach wall). People with fragile stomach will also suffer ulcer pains if Ibuprofen is taken.
  2. Hypertensive people: People who are one antihypertensive drug or the other especially drugs like Amlodipine, Nifedipine, Verapamil, Digoxin, Amiloride, Enalapril, Atenolol and Methyldopa are to stay away because the use of Ibuprofen prevents the drugs from lowering their blood pressure;  the blood pressure remains on the up level.
  3. People on some specific antibiotics: If you have infection and the doctor or pharmacist prescribes Quinolone- antibiotic drugs like Levofloxacin, Ofloxacin or Ciprofloxacin, you could convulse if taken with it. Ensure you seek advice if you are to take ibuprofen with any antibiotics; it can be very fatal when the side effects develops.
  4. Depressed Patients: If you have had some episodes of depression and you placed on antidepressant drug like Fluoxetine, can lead to bleeding from the orifices like the nose, mouth or vaginal. It can also lead to failure of the drugs when taken together or taken few hours after the use of fluoxetine.
  5. People taking another type of analgesics: a popular analgesic that mustn’t be used with Ibuprofen is Asprin; Aspirin has an antiplatelet activity in the body making it useful in prevention of stroke. If Ibuprofen is taken anytime with the drug, its ability to prevent stroke reduces.
  6. Patients taking steroidal anti-inflammatory drugs. They include Prednisolone, Dexamethasone (popularly called Xasten in Nigeria), Hydrocortisone; they are also used in the emergency treatment for an allergic reaction to any drug. Taking it with this medication could increase your blood pressure at that time.


It is very important you actively involve your Pharmacist when you are on a drug or when you want to take it any other medication. They remain the closest to you for good health to be guaranteed. Good health is best..



  1. The Complete Drug Formulary

Appendix 1

2017/2018 Edition

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